Understanding the Skin's Day and Night Cycle
The skin operates under a circadian rhythm, engaging in protective activities during the day and recovery processes at night.
Modern lifestyles, with irregular sleep and constant exposure to artificial light, disrupt these natural cycles, leading to skin issues such as premature ageing and reduced barrier function.
It is crucial to align skincare routines with these biological rhythms to enhance the effectiveness of treatments. By synchronizing skincare with the body’s natural cycles, products can more effectively support hydration, repair, and protection throughout the 24-hour cycle.
Enhancing Skin Health with Circadian Rhythms
The skin’s circadian rhythm regulates essential functions like cell regeneration, barrier repair, and hydration.
Chrono Chardy, with active compounds from Vitis Vinifera (Grape) Fruit Extract, modulates this cycle by influencing key circadian proteins: CLOCK, BMAL1, and PERIOD.
Chrono Chardy and Circadian Protein Interaction
CLOCK and BMAL1: These primary circadian regulators form a complex that coordinates cellular activities. Chrono Chardy enhances their stability and functionality, optimizing skin protection during the day and repair at night.
PERIOD Proteins: Essential for the circadian feedback loop, these proteins maintain regularity and prevent dysfunction. Chrono Chardy stabilizes PERIOD protein expression, supporting effective nighttime recovery and defence against environmental stress. Scientific Benefits of Chrono Chardy
By optimizing the functionality of circadian proteins, Chrono Chardy aligns with the skin's natural rhythms, boosting barrier function by day and enhancing recovery by night, fostering healthy skin.



